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Brain fMRI for Children and Adolescents with Complex Regional
Pain Syndrome (CRPS I and II)
Children and adolescents with Complex Regional Pain Syndrome
(CRPS I or II) may be eligible to participate in a clinical
research study conducted by the Children's Hospital Boston
and McLean Hospital in Belmont, Massachusetts.
Inclusion criteria
Patient must be 9-20 years old
Patient must have Complex Regional Pain Syndrome Type I or
II (CRPS I or II) affecting one lower extremity only
Summary
Each participant will first meet with a study clinician for
preliminary evaluation. Then, over the course of two separate
study sessions at the McLean Hospital Brain Imaging Center
in Belmont, Massachusetts (one session while the participant
is experiencing pain from CRPS and one when he/she is no long
experiencing pain) participants will take part in Quantitative
Sensory Testing (QST). QST is a safe and accurate method of
assessing an individual's sensitivity to touch and cold stimulation
on the skin. After initial sensory testing, the participant
will receive touch and cold stimulation on the skin during
functional MRI. Functional MRI is a safe and non-invasive
way of imaging the brain's structure and activation over brief
periods of time. In addition to providing a picture of the
brain, it shows how the brain responds to different levels
of stimulation, and will allow comparison of brain activity
between the pain and non-pain states. This study will promote
a better understanding of the brain's role in CRPS I and II.
Compensation/Expenses
Participants will receive a $30 gift certificate for each
of the two study sessions and a meal voucher for McLean Hospital
cafeteria. Parking at McLean Hospital is free.
No other travel expenses will be covered by the study staff.
For more information about this study, please
contact:
Dr. Alyssa LeBel, Neurologist, Children's Hospital Boston
or
Jennifer Jaskiewicz, Study Coordinator, Children's Hospital
Boston
Pain Treatment Service
333 Longwood Ave, 5th Floor
Boston, MA 02115
Tel: (617) 355 8973
Email:
jennifer.jaskiewicz@childrens.harvard.edu
Updated December 16, 2005 |
